Steven George

Education: 

B.S., Northwestern University, Chemical Engineering, 1987
M.D., University of Missouri-Columbia, 1991
Ph.D., University of Washington, 1995
Post-Doc, University of Washington, 1992-1995

Address: 

The Henry Samueli School of Engineering
University of California, Irvine
Irvine, CA 92697-2730

ZOT Code: 
2730
Location: 
Office: EH 2420
Lab: EH 2121
Phone: 
(949) 824-3941 Office
Fax: 
(949) 824-9968
Email: 
scgeorge@uci.edu
Research: 

Dr. George's work focuses on understanding the biology and physiology of the cardiopulmonary system. The approach integrates experimental observations and mathematical modeling. Within this context, he is pursuing two overarching areas of research, both of which combine cell, tissue, and whole organ studies: 1) prevascularization of implantable thick tissue constructs, 2) nitric oxide metabolism and 3) wound healing and tissue remodeling.

Dr. George and his group are working with Dr. Hughes in the School of Biological Sciences to prevascularize an implantable tissue construct with a network of mature interconnected capillaries that can rapidly anastomose with a host upon implantation. This project addresses a fundamental need in the field of tissue engineering – the creation of implantable tissues whose dimensions exceed the limit provided by diffusive transport alone. His lab is also working toward an understanding of what changes in the local biochemical environment affect nitric oxide exchange and tissue remodeling dynamics at the cellular and whole-organ level. The projects involve an understanding of the fluid mechanics of the bifurcating tubes, mass transfer coefficients, and biomechanics. Additional information on these and other projects can be found on his lab website.

Research topics: 
Physiological modeling, computational methods, tissue engineering.