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Current biochemical engineering research is directed at molecular level processes, the cell, tissues, the organism, and large-scale manufacturing in biochemical processes. Our department has extensive expertise in cloned gene expression, gene amplification and integration, metabolic engineering, bioseparation processes (including membrane and chromatographic separation), protein crystallization, bioreaction and bioreactor engineering, modeling, optimization and control of bioreactors, cell and tissue engineering, the biology and physiology of the human lung as an integrated, whole organ, wound healing and tissue remodeling.

Tissue engineering research at UC Irvine takes many forms, and involves active collaboration between chemical engineers and materials scientists with biomedical engineers, surgeons, and cell/molecular biologists. In the ChEMS department, fundamental research addressing the interactions between cells and novel biomaterials is being conducted in vitro, along with more applied research designed to engineer vascular networks into tissue constructs for implantation in vivo.



Featured Student


Himanshu Shama
, First-year Ph.D. Student
AdvisorsSzu-Wen Wang and Nancy DaSilva
"My research interest is in the areas of biomaterials, tissue engineering, and molecular biology.  Using recombinant technology, I am engineering yeast to create artificial biopolymers that can be used for medical applications, such as tissue regeneration and drug delivery."

Faculty 


Zhongping Chen
, Ph.D., Professor, Biomedical Engineering, Electrical Engineering and Computer Science, Chemical Engineering and Materials Science, Beckman Laser Institute
Research Interests:  Biomedical photonics, microfabrication, biomaterials, and biosensors. Fiber-optic based biomedical imaging systems development
Email: z2chen @ uci . edu


Nancy Da Silva
, Ph.D., Professor, Chemical Engineering and Materials Science and Biomedical Engineering
Research Interests:  Molecular biotechnology
Research Presentation Slides
Email
: ndasilva @ uci . edu


James Earthman
, Ph.D., Professor, Chemical Engineering and Materials Science and Biomedical Engineering
Research Interests:  Biomaterials, dental and orthopaedic implants, green materials, nanocrystalline alloys, and deformation and damage processes
Research Presentation Slides
Email: earthman @ uci . edu


Steven George
, M.D., Ph.D., William J. Link Professor and Chair, Biomedical Engineering and Chemical Engineering and Materials Science
Research Interests:  Physiological modeling, computational methods, tissue engineering
Email: scgeorge @ uci . edu


G. Wesley Hatfield
, Ph.D., Professor Emeritus of Microbiology and Molecular Genetics and Chemical Engineering and Materials Science
Research Interests:  Computationally optimized DNA assembly (CODA) and translational engineering technologies for the self-assembly of synthetic genes for optimal protein expression in non-native organism
Emailwes.hatfield @ uci . edu


Young Jik Kwon
, Ph.D., Assistant Professor, Chemical Engineering and Materials Science, Pharmaceutical Sciences, and Biomedical Engineering
Research Interests:  Gene therapy, drug delivery, cancer-targeted therapeutics, nanobiotechnology, tissue engineering
Research Presentation Slides
Email:  kwonyj @ uci . edu


G.P. Li
, Ph.D., Professor, Electrical Engineering and Computer Science, Biomedical Engineering, and Chemical Engineering and Materials Science
Research Interests:  High-speed semiconductor technology, micro-electro-mechanical systems (MEMS) technology, opto-electronic devices, and the design, fabrication and testing of integrated circuits
Email:  gpli @ uci . edu


Henry Lim
, Ph.D., Professor Emeritus, Chemical Engineering and Materials Science and Microbiology and Molecular Genetics
Research Interests:  Bioreaction and bioreactor engineering, modeling, optimization and control of bioreactors, cellular regulation, recombinant DNA technology, and bioremediation
Email: hclim @ uci . edu


Marc Madou
, Ph.D., Chancellor's Professor, Mechanical and Aerospace Engineering, Biomedical Engineering, and Chemical Engineering and Materials Science
Research Interests:  Miniaturization science (MEMS and NEMS) with emphasis on chemical and biological applications
Email: mmadou @ uci . edu


Hung Nguyen
, Ph.D., Assistant Professor, Chemical Engineering and Materials Science
Research Interests:  Self-assembly of biological and biomimetic nanoscale materials based on amino acids and on nucleic acids
Email:  hdn @ uci . edu


Kenneth Shea
, Ph.D., Professor, Chemistry and Chemical Engineering and Materials Science
Research Interests:  Developing new methods and strategies for synthesizing carbon-carbon bonds
Email: kjshea @ uci . edu


Vasan Venugopalan
, Sc.D., Associate Professor, Chemical Engineering and Materials Science and Biomedical Engineering
Research Interests:  Laser-induced thermal, mechanical and radiative transport processes for application in medical diagnostics, therapeutics, biotechnology, and micro-electro-mechanical systems (MEMS)
Email: vvenugop @ uci . edu


Szu-Wen Wang
, Ph.D., Assistant Professor, Chemical Engineering and Materials Science and Biomedical Engineering
Research Interests:  Combining principles of self-assembly with nature-inspired macromolecular systems to engineer new materials and therapeutic strategies
Research Presentation Slides
Email: wangsw @ uci . edu


H. Kumar Wickramasinghe
, Ph.D., The Henry Samueli Endowed Chair and Professor, Electrical Engineering and Computer Science, Biomedical Engineering, and Chemical Engineering and Materials Science
Research Interests: DNA sequencing techniques, nanotechnology
Email: hkwick @ uci . edu


Albert Yee
, Ph.D., Professor, Chemical Engineering and Materials Science, Biomedical Engineering, and Chemistry
Research Interests:  Materials science aspects of polymers and soft materials, particularly on how they are used to impact nanotechnology
Research Presentation Slides
Email: afyee @ uci . edu